Gallium-labelled peptides for imaging of inflammation

Eur J Nucl Med Mol Imaging. 2012 Feb:39 Suppl 1:S68-77. doi: 10.1007/s00259-011-1987-6.

Abstract

Inflammation plays a major role in the development of many diseases. This review article summarizes recent research in the field of in vivo imaging of inflammation. Novel methodologies using PET with (68)Ga peptides targeting, for example, vascular adhesion protein 1 are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amine Oxidase (Copper-Containing) / deficiency
  • Amine Oxidase (Copper-Containing) / genetics
  • Amine Oxidase (Copper-Containing) / metabolism
  • Animals
  • Atherosclerosis / diagnostic imaging
  • Cell Adhesion Molecules / deficiency
  • Cell Adhesion Molecules / genetics
  • Cell Adhesion Molecules / metabolism
  • Fracture Healing
  • Gallium Radioisotopes*
  • Humans
  • Infections / diagnostic imaging
  • Inflammation / diagnostic imaging*
  • Inflammation / metabolism
  • Integrin alphaVbeta3 / metabolism
  • Mice
  • Mice, Knockout
  • Neoplasms / diagnostic imaging
  • Oligopeptides
  • Peptides* / chemistry
  • Positron-Emission Tomography
  • Radiopharmaceuticals* / chemistry
  • Rats
  • Receptors, Somatostatin / metabolism

Substances

  • Cell Adhesion Molecules
  • Gallium Radioisotopes
  • Integrin alphaVbeta3
  • Oligopeptides
  • Peptides
  • Radiopharmaceuticals
  • Receptors, Somatostatin
  • arginyl-glycyl-aspartic acid
  • AOC3 protein, human
  • Amine Oxidase (Copper-Containing)
  • semicarbazide-sensitive amine oxidase-vascular adhesion protein-1, mouse