Separation of [18F]fluoride from [18O]water using anion exchange resin

D J Schlyer; M A Bastos; D Alexoff; A P Wolf

doi:10.1016/0883-2889(90)90034-e

Separation of [18F]fluoride from [18O]water using anion exchange resin

Int J Rad Appl Instrum A. 1990;41(6):531-3. doi: 10.1016/0883-2889(90)90034-e.

Authors

D J Schlyer¹, M A Bastos, D Alexoff, A P Wolf

Affiliation

¹ Department of Chemistry, Brookhaven National Laboratory, Upton, NY 11973.

PMID: 2163371
DOI: 10.1016/0883-2889(90)90034-e

Abstract

The separation of no carrier added [18F]fluoride from 18O enriched water is described. The [18F]fluoride is deposited on Dowex 1 x 10 anion exchange resin as the water is passed through. The 18F is removed by elution with a dilute solution of cesium carbonate or potassium carbonate in water. Recovery of the 18F is greater than 95% efficient with a loss of 18O water of less than 5 microL from a volume of 3 mL.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Anion Exchange Resins
Fluorine Radioisotopes / isolation & purification*
Oxygen Isotopes*
Water / analysis*

Substances

Anion Exchange Resins
Fluorine Radioisotopes
Oxygen Isotopes
Water

Grants and funding

NS-15380/NS/NINDS NIH HHS/United States