The production of [124I]iodine and [86Y]yttrium

Eur J Nucl Med Mol Imaging. 2011 May:38 Suppl 1:S4-9. doi: 10.1007/s00259-011-1782-4. Epub 2011 Apr 12.

Abstract

The use of paired tracers such as (124)I/(131)I and (86)Y/(90)Y allows pretherapy PET imaging with positron emitting radioisotopes of the same element as used for therapy. Whereas nowadays most therapy nuclides are produced by reactors or generators, the production of the corresponding PET isotopes requires the irradiation of adequate targets using particle accelerators such as cyclotrons. This paper describes the production routes for (124)I and (86)Y.

Publication types

  • Review

MeSH terms

  • Carbonates / chemistry*
  • Cyclotrons / instrumentation*
  • Half-Life
  • Indium Radioisotopes / chemistry*
  • Particle Accelerators / instrumentation*
  • Positron-Emission Tomography / methods
  • Radiopharmaceuticals / therapeutic use
  • Strontium / chemistry*
  • Tellurium / chemistry*
  • Yttrium Radioisotopes / chemistry*

Substances

  • Carbonates
  • Indium Radioisotopes
  • Radiopharmaceuticals
  • Yttrium Radioisotopes
  • tellurium dioxide
  • strontium carbonate
  • Tellurium
  • Strontium