Abstract
The essential steps are explained in calculating a radiation dose for radionuclide therapy from imaging data. As the dose alone is a meaningless value, its consequences in tumour cell kill efficiency and normal tissue damage are explained. The influence of dose rate and inhomogeneous dose distributions are discussed.
MeSH terms
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Cell Survival / radiation effects
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Dose-Response Relationship, Radiation
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Humans
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Models, Biological
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Neoplasms / radiotherapy*
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Radiobiology / statistics & numerical data
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Radiopharmaceuticals / administration & dosage
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Radiopharmaceuticals / adverse effects
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Radiopharmaceuticals / therapeutic use
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Radiotherapy / methods
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Radiotherapy / statistics & numerical data
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Radiotherapy Planning, Computer-Assisted / methods*
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Radiotherapy Planning, Computer-Assisted / statistics & numerical data