Cracking the moody brain: lifting the mood with ketamine

Nat Med. 2010 Dec;16(12):1384-5. doi: 10.1038/nm1210-1384.

Authors

James W Murrough¹, Dennis S Charney

Affiliation

¹ Mood and Anxiety Disorders Program, Mount Sinai School of Medicine, New York, New York, USA. james.murrough@mssm.edu

PMID: 21135850
DOI: 10.1038/nm1210-1384

No abstract available

MeSH terms

Antidepressive Agents / pharmacology*
Antidepressive Agents / therapeutic use
Depression / drug therapy*
Glutamic Acid / metabolism*
Humans
Ketamine / pharmacology*
Ketamine / therapeutic use
Models, Neurological
Protein Binding / drug effects
Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
Receptors, N-Methyl-D-Aspartate / metabolism
Signal Transduction / drug effects*
TOR Serine-Threonine Kinases / metabolism

Substances

Antidepressive Agents
Receptors, N-Methyl-D-Aspartate
Glutamic Acid
Ketamine
MTOR protein, human
TOR Serine-Threonine Kinases