Bioorthogonal small-molecule ligands for PARP1 imaging in living cells

Chembiochem. 2010 Nov 22;11(17):2374-7. doi: 10.1002/cbic.201000477.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Cell Nucleus / metabolism
  • Cytoplasm / metabolism
  • Green Fluorescent Proteins / genetics
  • Green Fluorescent Proteins / metabolism*
  • Humans
  • Kinetics
  • Ligands
  • Microscopy, Fluorescence / methods*
  • Molecular Structure
  • Phthalazines / chemistry*
  • Phthalazines / pharmacology
  • Piperazines / chemistry*
  • Piperazines / pharmacology
  • Poly (ADP-Ribose) Polymerase-1
  • Poly(ADP-ribose) Polymerase Inhibitors
  • Poly(ADP-ribose) Polymerases / genetics
  • Poly(ADP-ribose) Polymerases / metabolism*
  • Protein Transport / drug effects
  • Transfection
  • Xanthenes / chemistry

Substances

  • Ligands
  • Phthalazines
  • Piperazines
  • Poly(ADP-ribose) Polymerase Inhibitors
  • Xanthenes
  • Green Fluorescent Proteins
  • Texas red
  • PARP1 protein, human
  • Poly (ADP-Ribose) Polymerase-1
  • Poly(ADP-ribose) Polymerases
  • olaparib