Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine

Erik F J de Vries; Manel Roca; Francois Jamar; Ora Israel; Alberto Signore

doi:10.1007/s00259-010-1394-4

Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine

Eur J Nucl Med Mol Imaging. 2010 Apr;37(4):842-8. doi: 10.1007/s00259-010-1394-4.

Authors

Erik F J de Vries¹, Manel Roca, Francois Jamar, Ora Israel, Alberto Signore

Affiliation

¹ Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Abstract

We describe here a protocol for labelling autologous white blood cells with (99m)Tc-HMPAO based on previously published consensus papers and guidelines. This protocol includes quality control and safety procedures and is in accordance with current European Union regulations and International Atomic Energy Agency recommendations.

Publication types

Practice Guideline

MeSH terms

Cell Separation / methods
Chemotaxis, Leukocyte
Humans
Infections / diagnostic imaging
Inflammation / diagnostic imaging
Isotope Labeling / methods*
Leukocytes*
Quality Control
Radiation Protection / legislation & jurisprudence
Radiation Protection / methods
Radionuclide Imaging
Radiopharmaceuticals* / pharmacokinetics
Technetium Tc 99m Exametazime* / pharmacokinetics
Tissue Distribution

Substances

Radiopharmaceuticals
Technetium Tc 99m Exametazime