Abstract
A 22-month-old toddler presented with involuntary movements, hemiparesis, and behavioral changes. Magnetic resonance imaging showed no abnormality, but positron emission tomography (PET) showed focal hypermetabolism. By immunohistochemical technique with the patient's sera in control brain sections, autoantibodies recognizing the same areas as found by PET scanning were identified and disappeared after intravenous immunoglobulin therapy. PET scanning may be useful in the diagnosis of autoimmune encephalitis.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Autoantibodies / analysis
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Autoimmune Diseases / metabolism*
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Brain / metabolism*
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Encephalitis / drug therapy
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Encephalitis / metabolism*
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Female
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Humans
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Immunoglobulin G / immunology
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Immunoglobulins, Intravenous / administration & dosage
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Immunoglobulins, Intravenous / therapeutic use
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Immunohistochemistry
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Immunologic Factors / administration & dosage
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Immunologic Factors / therapeutic use
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Infant
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Magnetic Resonance Imaging
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Positron-Emission Tomography*
Substances
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Autoantibodies
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Immunoglobulin G
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Immunoglobulins, Intravenous
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Immunologic Factors