Personalized management of patients with inoperable alveolar echinococcosis undergoing treatment with albendazole: usefulness of positron-emission-tomography combined with serological and computed tomography follow-up

Clin Microbiol Infect. 2010 Jun;16(6):788-91. doi: 10.1111/j.1469-0691.2009.02924.x. Epub 2009 Nov 13.

Abstract

The present study aimed to identify a sub-group of inoperable alveolar echinococcosis (AE) patients undergoing long-term treatment with benzimidazole (BZM) who presented with an evolution suggestive of a parasitocidal effect. An evolution compatible with parasite death was observed in five patients.

MeSH terms

  • Adult
  • Albendazole / therapeutic use*
  • Animals
  • Anthelmintics / therapeutic use*
  • Antibodies, Helminth / blood
  • Drug Monitoring / methods*
  • Echinococcosis
  • Echinococcosis, Hepatic / diagnosis
  • Echinococcosis, Hepatic / drug therapy
  • Echinococcus / immunology
  • Enzyme-Linked Immunosorbent Assay / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Positron-Emission Tomography / methods
  • Radiography, Abdominal / methods
  • Serologic Tests
  • Tomography, X-Ray Computed / methods

Substances

  • Anthelmintics
  • Antibodies, Helminth
  • Albendazole

Supplementary concepts

  • Alveolar echinococcosis