Utility of detailed preoperative cardiac testing and incidence of post-thoracotomy myocardial infarction

J Thorac Cardiovasc Surg. 2008 Mar;135(3):648-55. doi: 10.1016/j.jtcvs.2007.09.021.

Abstract

Objective: Recent literature has questioned the efficacy of routine detailed preoperative cardiac ischemia testing and preoperative cardiac intervention before noncardiac surgical procedures.

Methods: We performed a retrospective review of patients undergoing thoracotomy (n = 294) between January of 1999 and January of 2005.

Results: The median age was 62 years. Detailed preoperative cardiac testing was performed on 184 patients (63%) and went beyond a thorough history, physical examination, and electrocardiogram to include at least one of the following: dobutamine stress echo (n = 116), nuclear stress test (n = 66), treadmill test (n = 8), and coronary angiogram (n = 40). Evidence for coronary disease was detected in 43% of tests (99/230) performed. Revascularization was performed in 10% of all patients (4/40) who underwent coronary angiography. Postoperative myocardial infarction occurred in 7 patients (2.4%) with 4 myocardial infarction-related mortalities. No significant difference was found in the incidence of myocardial infarction in patients with (n = 184) or without (n = 110) detailed preoperative cardiac testing (3.3% vs 0.9%, P = .29). Of the 4 patients (1.4%) who underwent revascularization to treat coronary lesions identified during prethoracotomy workup, 2 had a myocardial infarction, 1 of which was caused by thrombosis of a coronary stent. In the subset of patients who underwent lobectomy (n = 149), detailed cardiac testing was performed on 107 patients (72%). The incidence of myocardial infarction was similar in tested and untested patients (2.8% vs 2.4% respectively, P = 1.0).

Conclusion: Selective use of detailed preoperative cardiac testing refines risk stratification and identifies patients for corrective cardiac interventions; however, it did not prove fully protective against myocardial infarction after thoracotomy in our study.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon, Coronary / methods
  • Cardiac Catheterization / methods
  • Cohort Studies
  • Coronary Angiography / methods
  • Echocardiography, Stress / methods
  • Female
  • Follow-Up Studies
  • Heart Function Tests
  • Humans
  • Incidence
  • Lung Neoplasms / mortality
  • Lung Neoplasms / pathology
  • Lung Neoplasms / surgery*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Infarction / diagnosis*
  • Myocardial Infarction / epidemiology*
  • Myocardial Infarction / therapy
  • Myocardial Ischemia / diagnosis
  • Myocardial Ischemia / epidemiology
  • Myocardial Ischemia / therapy
  • Neoplasm Staging
  • Postoperative Complications / prevention & control
  • Preoperative Care / methods*
  • Probability
  • Retrospective Studies
  • Risk Assessment
  • Sex Distribution
  • Survival Analysis
  • Thoracotomy / adverse effects*
  • Thoracotomy / methods