Controversies in nephrology: renal albumin handling, facts, and artifacts!

Kidney Int. 2007 Nov;72(10):1192-4. doi: 10.1038/sj.ki.5002526. Epub 2007 Sep 5.

Abstract

In this article, we discuss and contradict a recent publication by Russo et al., which suggests that the filtration of large amounts of albumin followed by transtubular transport of intact albumin is a physiological phenomenon.

Publication types

  • Comment
  • Review

MeSH terms

  • Albumins / metabolism*
  • Albumins / ultrastructure
  • Animals
  • Artifacts*
  • Autoradiography
  • Biological Transport
  • Endocytosis
  • Glomerular Filtration Rate
  • Iodine Radioisotopes / metabolism
  • Kidney / chemistry*
  • Kidney / physiology*
  • Kidney Tubules, Proximal / physiology
  • Kidney Tubules, Proximal / ultrastructure
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Albumins
  • Iodine Radioisotopes