Bone regeneration: molecular and cellular interactions with calcium phosphate ceramics

Int J Nanomedicine. 2006;1(3):317-32.

Abstract

Calcium phosphate bioceramics are widely used in orthopedic and dental applications and porous scaffolds made of them are serious candidates in the field of bone tissue engineering. They have superior properties for the stimulation of bone formation and bone bonding, both related to the specific interactions of their surface with the extracellular fluids and cells, ie, ionic exchanges, superficial molecular rearrangement and cellular activity.

Publication types

  • Review

MeSH terms

  • Animals
  • Bone Regeneration / physiology*
  • Bone Substitutes / chemistry*
  • Calcium Phosphates / chemistry*
  • Cells, Cultured
  • Ceramics / chemistry*
  • Humans
  • Osseointegration / physiology
  • Osteoblasts / cytology*
  • Osteoblasts / physiology*
  • Osteogenesis / physiology
  • Tissue Engineering / methods*

Substances

  • Bone Substitutes
  • Calcium Phosphates
  • calcium phosphate