RBE and w(R) values of Auger emitters and low-range beta emitters with particular reference to tritium

J Radiol Prot. 2007 Jun;27(2):157-68. doi: 10.1088/0952-4746/27/2/003. Epub 2007 May 24.

Abstract

An apparent disparity exists between RBE (relative biological effectiveness) values for low-range beta and Auger emitters, and the current value for their radiation weighting factor (w(R)). This paper presents evidence that the current w(R) value of unity for these nuclides is inconsistent with most RBE evidence and should be increased by a factor of two to three. It recommends that the ICRP should clearly state that the most appropriate RBE value for these nuclides, and not the w(R) value, should be used in specific dose calculations, retrospective dose estimations and epidemiological studies. The ICRP should also publish guidance as to the methods and data sources that could be used for these RBE values.

MeSH terms

  • Beta Particles
  • Electrons
  • Humans
  • Practice Guidelines as Topic
  • Radiation Dosage*
  • Radiation Effects
  • Radiation Monitoring
  • Radiation Protection
  • Radiation, Ionizing*
  • Radiometry
  • Radiopharmaceuticals / adverse effects
  • Relative Biological Effectiveness*
  • Risk Assessment
  • Tritium* / adverse effects

Substances

  • Radiopharmaceuticals
  • Tritium