Organ dose conversion coefficients for voxel models of the reference male and female from idealized photon exposures

Phys Med Biol. 2007 Apr 21;52(8):2123-45. doi: 10.1088/0031-9155/52/8/006. Epub 2007 Mar 26.

Abstract

A new series of organ equivalent dose conversion coefficients for whole body external photon exposure is presented for a standardized couple of human voxel models, called Rex and Regina. Irradiations from broad parallel beams in antero-posterior, postero-anterior, left- and right-side lateral directions as well as from a 360 degrees rotational source have been performed numerically by the Monte Carlo transport code EGSnrc. Dose conversion coefficients from an isotropically distributed source were computed, too. The voxel models Rex and Regina originating from real patient CT data comply in body and organ dimensions with the currently valid reference values given by the International Commission on Radiological Protection (ICRP) for the average Caucasian man and woman, respectively. While the equivalent dose conversion coefficients of many organs are in quite good agreement with the reference values of ICRP Publication 74, for some organs and certain geometries the discrepancies amount to 30% or more. Differences between the sexes are of the same order with mostly higher dose conversion coefficients in the smaller female model. However, much smaller deviations from the ICRP values are observed for the resulting effective dose conversion coefficients. With the still valid definition for the effective dose (ICRP Publication 60), the greatest change appears in lateral exposures with a decrease in the new models of at most 9%. However, when the modified definition of the effective dose as suggested by an ICRP draft is applied, the largest deviation from the current reference values is obtained in postero-anterior geometry with a reduction of the effective dose conversion coefficient by at most 12%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Body Burden
  • Computer Simulation
  • Female
  • Germany
  • Humans
  • Male
  • Models, Biological*
  • Organ Specificity*
  • Photons*
  • Radiation Dosage
  • Reference Values
  • Relative Biological Effectiveness*
  • Whole-Body Counting / methods*
  • Whole-Body Counting / standards*