Usefulness of 18-fluorodeoxyglucose positron emission tomography in the evaluation of tumor cardiac thrombus from renal cell carcinoma

Clin Transl Oncol. 2006 Feb;8(2):124-8. doi: 10.1007/s12094-006-0169-7.

Abstract

Purpose: Retrospectively analysed our experience in Renal Cell carcinoma (RCC) patients studied with 18-Fluorodeoxyglucose Positron Emission Tomography (FDG PET) to rule out the incidence and clinical impact of heart metastases.

Material and methods: In two years, 37 patients with RCC were studied with FDG PET. 10 were studied for initial staging and 27 patients were evaluated for suspected recurrence or re-staging.

Results: In two patients (5%), PET scan showed pathological focal uptake in myocardium. On the bases of this finding, MRI was performed visualizing a myocardial mass in both lesions and confirmed by histology in one of them. The hypothesis of prolepses of the tumour by thrombus in RCC patients justified the surgery.

Conclusion: Whole-body FDG PET in RCC patients could help to diagnose cardiac metastasis, and allows the possibility of therapeutic surgery, due to the thrombus significance of heart involvement.

Publication types

  • Case Reports
  • Evaluation Study

MeSH terms

  • Carcinoma, Renal Cell / diagnostic imaging*
  • Diagnosis, Differential
  • Fluorodeoxyglucose F18*
  • Heart Neoplasms / diagnostic imaging*
  • Heart Neoplasms / pathology
  • Heart Neoplasms / secondary*
  • Humans
  • Kidney Neoplasms / diagnostic imaging*
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / secondary
  • Magnetic Resonance Imaging, Cine
  • Male
  • Middle Aged
  • Neoplasm Staging / methods
  • Positron-Emission Tomography*
  • Radiopharmaceuticals*
  • Vena Cava, Inferior
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / etiology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18