How we do it: surgery should be considered equally with I131 and thionamide treatment as first-line therapy for thyrotoxicosis

Clin Otolaryngol. 2006 Apr;31(2):160-2. doi: 10.1111/j.1749-4486.2006.01150.x.

Abstract

Radioiodine and thionamide treatment are the most frequently used treatment modalities for thyrotoxicosis in Europe and North America with surgery being reserved for selected cases. * In our clinic patients were offered all three modalities via simultaneous interview with an endocrinologist and a surgeon, with international risk benefit data for radioiodine and thionamide therapy, and local risk benefit data for total thyroidectomy provided. * When given the choice, at least 15% of patients opted for total thyroidectomy over the other modalities. * In our series of 100 consecutive surgical patients there was a 4% malignancy rate. * Total thyroidectomy should be offered equally, with radioiodine and thionamide treatment, as a first line treatment modality in the management of thyrotoxicosis.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antithyroid Agents / therapeutic use*
  • Female
  • Humans
  • Iodine Radioisotopes / therapeutic use*
  • Male
  • Middle Aged
  • Thyroidectomy*
  • Thyrotoxicosis / surgery
  • Thyrotoxicosis / therapy*
  • Treatment Outcome

Substances

  • Antithyroid Agents
  • Iodine Radioisotopes