Multidetector computed tomography and neuroendocrine pancreaticoduodenal tumors

Acta Radiol. 2006 Apr;47(3):248-56. doi: 10.1080/02841850600550716.

Abstract

Purpose: To investigate the accuracy of dedicated pancreatic multidetector computed tomography (MDCT) in the diagnosis of neuroendocrine pancreaticoduodenal tumors (NPTs).

Material and methods: MDCT and other imaging studies in patients with suspected NPTs were identified. Thirty dedicated MDCT studies were done in 23 patients. Fourteen patients (16 operations) subsequently had surgery. Imaging reports were reviewed and findings compared with surgical findings and findings in other imaging studies.

Results: Patients with surgery: 19 NPTs (16 extrapancreatic gastrinomas and 3 pancreatic NPTs) were identified at surgery. MDCT identified 16 and somatostatin receptor scintigraphy (SRS) 11 out of 19 tumors. Endoscopic ultrasound detected 11 out of 14 NPTs. Patients without surgery: In 4 out of 9 patients, no NPTs were identified at MDCT.

Conclusion: Dedicated MDCT of the pancreas can identify many NPTs, including small duodenal and periduodenal tumors, and the detection rate is better than reported in the older literature on CT.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Islet Cell / diagnosis
  • Carcinoma, Islet Cell / diagnostic imaging*
  • Carcinoma, Islet Cell / surgery
  • Duodenal Neoplasms / diagnosis
  • Duodenal Neoplasms / diagnostic imaging*
  • Duodenal Neoplasms / surgery
  • Female
  • Humans
  • Insulinoma / diagnosis
  • Insulinoma / diagnostic imaging*
  • Insulinoma / surgery
  • Male
  • Middle Aged
  • Neuroendocrine Tumors / diagnosis
  • Neuroendocrine Tumors / diagnostic imaging*
  • Neuroendocrine Tumors / surgery
  • Pancreatic Neoplasms / diagnosis
  • Pancreatic Neoplasms / diagnostic imaging*
  • Pancreatic Neoplasms / surgery
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed*