Exploiting tumour hypoxia in cancer treatment

Nat Rev Cancer. 2004 Jun;4(6):437-47. doi: 10.1038/nrc1367.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Bacteria, Anaerobic / physiology
  • Cell Hypoxia*
  • DNA-Binding Proteins / pharmacology
  • DNA-Binding Proteins / therapeutic use*
  • Drug Resistance, Neoplasm
  • Genetic Therapy*
  • Helix-Loop-Helix Motifs
  • Humans
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Necrosis
  • Neoplasms / physiopathology*
  • Neoplasms / therapy*
  • Nuclear Proteins / pharmacology
  • Nuclear Proteins / therapeutic use*
  • Prodrugs*
  • Transcription Factors

Substances

  • DNA-Binding Proteins
  • HIF1A protein, human
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Nuclear Proteins
  • Prodrugs
  • Transcription Factors