A 3D high-resolution gamma camera for radiopharmaceutical studies with small animals

Appl Radiat Isot. 2003 Apr;58(4):501-8. doi: 10.1016/s0969-8043(03)00025-3.

Abstract

The results of studies conducted with a small field of view tomographic gamma camera based on a Position Sensitive Photomultiplier Tube are reported. The system has been used for the evaluation of radiopharmaceuticals in small animals. Phantom studies have shown a spatial resolution of 2mm in planar and 2-3mm in tomographic imaging. Imaging studies in mice have been carried out both in 2D and 3D. Conventional radiopharmaceuticals have been used and the results have been compared with images from a clinically used system.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Animals
  • Bombesin / pharmacokinetics*
  • Gamma Cameras
  • Image Processing, Computer-Assisted / instrumentation
  • Kidney / diagnostic imaging
  • Mice
  • Mice, Nude
  • Neoplasms, Experimental / diagnostic imaging*
  • Radionuclide Imaging
  • Radiopharmaceuticals / pharmacokinetics*
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted / instrumentation
  • Technetium / chemistry
  • Technetium / pharmacokinetics*

Substances

  • Radiopharmaceuticals
  • Technetium
  • Bombesin