[11C]Formaldehyde revisited: considerable concurrent [11C]formic acid formation in the low-temperature conversion of

D Roeda; C Crouzel

doi:10.1016/s0969-8043(00)00352-3

[11C]Formaldehyde revisited: considerable concurrent [11C]formic acid formation in the low-temperature conversion of

Appl Radiat Isot. 2001 Jun;54(6):935-9. doi: 10.1016/s0969-8043(00)00352-3.

Authors

D Roeda¹, C Crouzel

Affiliation

¹ Service Hospitalier Frédéric Joliot, Département de Recherche Médicale, CEA, Orsay, France. roeda@dsvidf.cea.fr

PMID: 11300407
DOI: 10.1016/s0969-8043(00)00352-3

Abstract

The reduction of [11C]carbon dioxide with lithium aluminium hydride in diethyl ether at temperatures ranging from -56 degrees C to 19 degrees C was studied. In contrast to what others have reported, considerable amounts of [11C]formic acid were found at all studied temperatures.

MeSH terms

Carbon Dioxide*
Carbon Radioisotopes*
Formaldehyde / chemical synthesis*
Formaldehyde / chemistry
Formates / chemical synthesis*
Formates / chemistry
Radiopharmaceuticals / chemical synthesis

Substances

Carbon Radioisotopes
Formates
Radiopharmaceuticals
formic acid
Carbon Dioxide
Formaldehyde