Positron emission tomography with (18)F-fluorodeoxyglucose of uterine sarcoma: a comparison with magnetic resonance imaging and power Doppler imaging

Gynecol Oncol. 2001 Mar;80(3):372-7. doi: 10.1006/gyno.2000.6081.

Abstract

Objective: The effectiveness of positron emission tomography with (18)F-fluorodeoxyglucose (FDG-PET) for diagnosis of uterine sarcoma was evaluated in comparison to the effectiveness of magnetic resonance (MR) imaging and power Doppler imaging.

Method: The cases of five Osaka City University Hospital patients diagnosed with uterine sarcoma based on histopathological examination, in whom FDG-PET, MR imaging, and power Doppler imaging studies had been performed preoperatively, were reviewed. A comparative study of the usefulness of these three imaging modalities for diagnosis of sarcoma was conducted. Tumors comprised three leiomyosarcomas, one endometrial stromal sarcoma, and one carcinosarcoma.

Results: FDG-PET examinations were 100% positive for the five sarcomas; MR imagings were 80% positive (four of five cases), and US was 40% positive (two of five cases). The mean standardized uptake value of the sarcomas was 4.5 +/- 1.3.

Conclusion: The sarcoma lesions were clearly imaged by FDG-PET. FDG-PET may be a most useful diagnostic method for uterine sarcoma.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Carcinosarcoma / diagnostic imaging*
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Leiomyosarcoma / diagnostic imaging*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Radiography
  • Radiopharmaceuticals*
  • Sarcoma, Endometrial Stromal / diagnostic imaging*
  • Tomography, Emission-Computed
  • Ultrasonography, Doppler
  • Uterine Neoplasms / diagnostic imaging*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18