Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents

J Med Chem. 2000 Sep 21;43(19):3453-73. doi: 10.1021/jm000022w.
No abstract available

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Animals
  • Antibodies, Monoclonal / biosynthesis
  • Antibodies, Monoclonal / chemistry
  • Antibodies, Monoclonal / therapeutic use
  • Clinical Trials as Topic
  • Drug Design
  • Fibrinolytic Agents / chemical synthesis*
  • Fibrinolytic Agents / chemistry
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Injections
  • Integrins / antagonists & inhibitors*
  • Molecular Mimicry
  • Peptides / chemistry
  • Peptides / isolation & purification
  • Peptides / therapeutic use
  • Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
  • Snake Venoms / chemistry

Substances

  • Antibodies, Monoclonal
  • Fibrinolytic Agents
  • Integrins
  • Peptides
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Snake Venoms