An appraisal of 18-fluorodeoxyglucose positron emission tomography for melanoma staging

Dermatology. 2000;200(2):167-9. doi: 10.1159/000018357.

Abstract

Background: Positron emission tomography (PET scan) using fluorodeoxyglucose (FDG) is increasingly recognized as a reliable diagnostic method to detect metastases of malignant melanoma (MM).

Objective: To compare the diagnostic performance of 18-FDG PET scan to that of conventional imaging.

Methods: A total of 28 assessments were conducted in 24 patients at risk of metastatic MM.

Results: The diagnostic accuracy was over 80% and similar for PET scan and conventional imaging.

Conclusion: Both the specificity and sensitivity of PET scan are high although not perfect. Confrontation of data with anatomical location and clinicopathological findings remains mandatory.

MeSH terms

  • Humans
  • Melanoma / diagnostic imaging*
  • Melanoma / pathology
  • Melanoma / secondary*
  • Radiopharmaceuticals*
  • Sensitivity and Specificity
  • Tomography, Emission-Computed*

Substances

  • Radiopharmaceuticals