MRI in recurrent nasopharyngeal carcinoma

Neuroradiology. 1999 Nov;41(11):855-62. doi: 10.1007/s002340050857.

Abstract

In this study, we retrospectively reviewed the MRI features of recurrent nasopharyngeal carcinoma (NPC) in 72 patients who underwent MRI before and after gadolinium injection. Recurrent NPC exhibited a high degree of regional spread and a variety of signal intensities and contours. MRI showed a nasopharyngeal mass in 50 patients (69.4 %); other sites of involvement included the parapharyngeal space (44.4 %), nasal cavity (12.5 %), paranasal sinuses (27.8 %), oropharynx (4.2 %), orbit (8.3 %), infratemporal fossa (18.1 %), skull base (59.8 %), intracranial area (51.4 %) and regional lymph nodes (15.3 %). On T2-weighted images, the nasopharyngeal mass gave high signal in 9 of 50 cases (18 %), intermediate in 27 (54 %), mixed in 8 (16 %) and low signal in 6 (12 %). Contrast enhancement was strong in 12 cases (24 %), moderate in 29 (58 %) and heterogeneous in 9 (18 %). The lesion was convex in 31 cases (62 %) and concave or straight in 19 (38 %). Recognition of the distribution and the appearance of recurrent NPC on MRI is essential for timely diagnosis and appropriate treatment.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma / diagnosis*
  • Carcinoma / pathology
  • Carcinoma / secondary
  • Contrast Media
  • Female
  • Follow-Up Studies
  • Gadolinium DTPA
  • Humans
  • Image Enhancement
  • Lymphatic Metastasis
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Nasal Cavity / pathology
  • Nasopharyngeal Neoplasms / diagnosis*
  • Nasopharyngeal Neoplasms / pathology
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local / diagnosis*
  • Neoplasm Recurrence, Local / pathology
  • Nose Neoplasms / diagnosis
  • Paranasal Sinus Neoplasms / diagnosis
  • Pharyngeal Neoplasms / diagnosis
  • Retrospective Studies
  • Skull Base Neoplasms / diagnosis
  • Skull Neoplasms / diagnosis

Substances

  • Contrast Media
  • Gadolinium DTPA