Meeting Report
Banff 07 Classification of Renal Allograft Pathology: Updates and Future Directions

https://doi.org/10.1111/j.1600-6143.2008.02159.xGet rights and content
Under a Creative Commons license
open archive

The 9th Banff Conference on Allograft Pathology was held in La Coruna, Spain on June 23–29, 2007. A total of 235 pathologists, clinicians and scientists met to address unsolved issues in transplantation and adapt the Banff schema for renal allograft rejection in response to emerging data and technologies. The outcome of the consensus discussions on renal pathology is provided in this article. Major updates from the 2007 Banff Conference were: inclusion of peritubular capillaritis grading, C4d scoring, interpretation of C4d deposition without morphological evidence of active rejection, application of the Banff criteria to zero-time and protocol biopsies and introduction of a new scoring for total interstitial inflammation (ti-score). In addition, emerging research data led to the establishment of collaborative working groups addressing issues like isolated ‘v’ lesion and incorporation of omics-technologies, paving the way for future combination of graft biopsy and molecular parameters within the Banff process.

Key words

Acute allograft rejection
acute cellular rejection
acute rejection
allograft rejection
antibody-mediated rejection
Banff
Banff lesions
Banff schema
classification
chronic allograft nephropathy
chronic allograft rejection
genomic markers
GeneChip

Abbreviations

ABMR
antibody-mediated rejection
AB0I
AB0-incompatible
ATN
acute tubular necrosis
+CM
positive HLA cross-match
DSA
donor specific antibody
FSGS
focal segmental glomerulosclerosis
IF
immunofluorescence
IF/TA
interstitial fibrosis and tubular atrophy
IHC
immunohistochemistry
PBT
pathogenesis based transcript set
PTC
peritubular capillaries
Ptc
peritubular capillaritis
SCr
serum creatinine
SR
subclinical rejection
TCMR
T cell-mediated rejection
TG
transplant glomerulopathy

Cited by (0)