Glucose uptake, glucose transporter GLUT4, and glycolytic enzymes in brown adipose tissue from rats adapted to a high-protein diet☆
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Peripheral blood mononuclear cells as a source to detect markers of homeostatic alterations caused by the intake of diets with an unbalanced macronutrient composition
2015, Journal of Nutritional BiochemistryCitation Excerpt :This is further confirmed by decreased expression of two key glycolytic genes, Gapdh and Hk1, and of Glut4, which facilitates cellular glucose uptake. A decreased activity of key glycolytic enzymes and a decrease in GLUT4 content have been previously reported as an adaptation to an HP diet in other tissues, such as brown adipose tissue [62]. In addition, two other genes involved in lipid metabolism/adipogenesis were affected in PBMCs as a result of the intake of an HP diet, Dhrs3 and Pref-1.
The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats
2012, Metabolism: Clinical and ExperimentalCitation Excerpt :The procedure and the technique for NE measurement have been described in detail [20]. The procedure, which was based on the method of Sokoloff et al [21] and modified by Ferré et al [22], has been previously described [23]. Briefly, 30 μCi (11 Ci/mmol) of 2-deoxy-1-[14 C]glucose (2-DG) in 0.5 mL of 0.9% NaCl was injected intravenously, and serial blood samples were collected to determine the concentrations of glucose and 2-DG (in terms of radioactivity).
Pitfalls in positron emission tomography/computed tomography imaging: Causes and their classifications
2009, Chinese Medical Sciences JournalDetermination of Age-Related Changes in Structure and Function of Skin, Adipose Tissue, and Skeletal Muscle With Computed Tomography, Magnetic Resonance Imaging, and Positron Emission Tomography
2007, Seminars in Nuclear MedicineCitation Excerpt :These different locations of white adipose tissue are distinguishable by cross-sectional imaging using CT or magnetic resonance imaging (MRI).25 Brown adipose tissue plays an important role in cold-induced and diet-induced thermogenesis.26 The brown color is attributed to high vascularity and mitochondrial density.
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Supported by grants from the Funda[ccedil][atilde]o de Amparo [agrave] Pesquisa do Estado de S[atilde]o Paulo (FAPESP no. 01/10050-8) and Conselho Nacional de Desenvolvimento Cient[iacute]fico e Tecnol[oacute]gico (CNPq no. 510923/93-3)