Regular ArticlesFerumoxide-enhanced magnetic resonance imaging techniques in pre-operative assessment for colorectal liver metastases
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Cited by (33)
Preclinical Evaluation and Clinical Translation of Magnetite-Based Nanomedicines
2019, Journal of Drug Delivery Science and TechnologyThe impact of staging laparoscopy prior to hepatic resection for colorectal metastases
2007, European Journal of Surgical OncologyCitation Excerpt :The value of these resections is dependant on accurate perioperative imaging to ensure isolated hepatic disease as well as the absence of peritoneal and extrahepatic nodal disease as patients with unresectable extrahepatic disease do not benefit from a liver resection.9 Cross-sectional CT, MRI and very recently PET scanning have been used in the preoperative staging prior to a planed liver resection for colorectal metastatic disease.10–12 However, despite advances in cross-sectional imaging up to 20% of patients with colorectal hepatic metastases have undiagnosed extrahepatic disease and are therefore unsuitable for resection.13
Surgical therapy for colorectal metastases to the liver
2007, Journal of Gastrointestinal SurgeryPreoperative Imaging for Metastasectomy
2007, Surgical Oncology Clinics of North AmericaCitation Excerpt :CTAP is an invasive procedure requiring arterial catheterization of the superior mesenteric artery or the splenic artery. Multiple studies have shown a similar sensitivity and superior specificity of MRI over CTAP [47,54,55]. A recent small trial of mostly colorectal and breast cancer patients has shown superiority of Gd-MR arterial portography over CTAP in liver lesion sensitivity and specificity [56].
Radiological staging of colorectal liver metastases
2007, Surgical OncologyCitation Excerpt :Sensitivities with SPIO-enhanced scan have been reported at 95% [37–39]. Limitations of SPIO such as Endorem (Guerbet) include a long infusion time (30 min), which prolongs study time and may be associated with significant side effects, such as low back pain and hypotension that has been reported in 10–15% of patients [38–43]. Mangafodipir trisodium (MnDPDP, TeslaScan, GE Healthcare) is a hepatocytes specific, positive contrast agent, taken up by hepatocytes after intravenous administration and the normal liver parenchyma shows increased signal on T1-weighted images while metastases are hypointense.
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Correspondence to: J. R. M. van der Sijp, MD, PhD, VU Medical Centre, Department of Surgery, PO Box 7057, 1007 MB Amsterdam, The Netherlands. Tel: +31-20-4444-535; Fax: +31-20-4444-512; E-mail: [email protected]