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Visual stimuli activate auditory cortex in the deaf

Abstract

Previous brain imaging studies have demonstrated responses to tactile and auditory stimuli in visual cortex of blind subjects, suggesting that removal of one sensory modality leads to neural reorganization of the remaining modalities1,2,3. To investigate whether similar 'cross-modal' plasticity occurs in human auditory cortex, we used functional magnetic resonance imaging (fMRI) to measure visually evoked activity in auditory areas of both early-deafened and hearing individuals. Here we find that deaf subjects exhibit activation in a region of the right auditory cortex, corresponding to Brodmann's areas 42 and 22, as well as in area 41 (primary auditory cortex), demonstrating that early deafness results in the processing of visual stimuli in auditory cortex.

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Figure 1: Visual stimuli activate auditory cortex in the deaf.
Figure 2: Mean activation in deaf versus hearing subjects to visual stimuli.

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References

  1. Sadato, N. et al. Nature 380, 526–528 (1996).

    Article  CAS  Google Scholar 

  2. Weeks, R. et al. J. Neurosci. 20, 2664–2672 (2000).

    Article  CAS  Google Scholar 

  3. Kujala, T. et al. Trends Neurosci 23, 115–120 (2000).

    Article  CAS  Google Scholar 

  4. Cox, R. W. Computers and Biomedical Research 29, 162–173 (1996).

    Article  CAS  Google Scholar 

  5. Talairach, J. & Tournoux, P. Co-Planar Stereotaxic Atlas of the Human Brain (Thieme Medical, New York, 1988).

    Google Scholar 

  6. Christman, S. Cerebral Asymmetries in Sensory and Perceptual Processing (Elsevier Science B.V., 1997).

    Google Scholar 

  7. Westbury, C. F. et al. Cereb. Cortex 9, 392–405 (1999).

    Article  CAS  Google Scholar 

  8. Rademacher, J. et al. Neuroimage 13, 669–683 (2001).

    Article  CAS  Google Scholar 

  9. Martinez, A. et al. Nat. Neurosci. 2, 364–369 (1999).

    Article  CAS  Google Scholar 

  10. Gandhi, S. P. et al. Proc. Natl. Acad. Sci. USA 96, 3314–3319 (1999).

    Article  CAS  Google Scholar 

  11. Petitto, L.A. et al. Proc. Natl. Acad. Sci. USA 97, 13961–13966 (2000).

    Article  CAS  Google Scholar 

  12. Nishimura, H. et al. Nature 397, 116 (1999).

    Article  CAS  Google Scholar 

  13. Calvert, G. A. et al. Science 276, 593–596 (1997).

    Article  CAS  Google Scholar 

  14. Neville, H. J. Ann. NY Acad. Sci. 608, 71–91 (1990).

    Article  CAS  Google Scholar 

  15. Baumgart, F. et al. Nature 400, 724–726 (1999).

    Article  CAS  Google Scholar 

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Acknowledgements

Supported by an NSF grant to K.R.D. and an NRSA grant to E.M.F. We thank G. Boynton and M. Sereno for helpful discussions, G. Brown, L. Eyler Zorrilla, P. Goldin and S. Tapert for assistance with data analysis, and D. Cai for assistance with subject recruitment.

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Correspondence to Karen R. Dobkins.

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Finney, E., Fine, I. & Dobkins, K. Visual stimuli activate auditory cortex in the deaf. Nat Neurosci 4, 1171–1173 (2001). https://doi.org/10.1038/nn763

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