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Tracking gene and cell fate for therapeutic gain

Nature Materials volume 13, pages 106–109 (2014)Cite this article

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The preclinical intersection of molecular imaging and gene- and cell-based therapies will enable more informed and effective clinical translation. We discuss how imaging can monitor cell and gene fate and function in vivo and overcome barriers associated with these therapies.

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Figure 1: Pathways in gene- and cell-based therapies.

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Acknowledgements

This work was supported in part by grants from NIH R01 HL093172, NIH R01 EB009689, NIH R01 HL095571, CIRM DR2-05394 and CIRM TR3-05556 (J.C.W).

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Authors and Affiliations

  1. Stanford Cardiovascular Institute, 265 Campus Drive, Room G1120B, Stanford, 94305-5454, California, USA

    Nigel G. Kooreman, Julia D. Ransohoff & Joseph C. Wu

  2. Departments of Medicine and Radiology (Molecular Imaging Program), 265 Campus Drive, Room G1120B, Stanford, 94305-5454, California, USA

    Nigel G. Kooreman, Julia D. Ransohoff & Joseph C. Wu

  3. Institute of Stem Cell Biology and Regenerative Medicine, 265 Campus Drive, Room G1120B, Stanford, 94305-5454, California, USA

    Joseph C. Wu

Authors
  1. Nigel G. Kooreman
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  2. Julia D. Ransohoff
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  3. Joseph C. Wu
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Contributions

All authors contributed equally to this manuscript.

Corresponding author

Correspondence to Joseph C. Wu.

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Kooreman, N., Ransohoff, J. & Wu, J. Tracking gene and cell fate for therapeutic gain. Nature Mater 13, 106–109 (2014). https://doi.org/10.1038/nmat3868

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