Abstract
Glutathione S-transferase Pi (GST P) has been reported to be a marker of dysplastic lesions. For this reason expression of GST P by intraduct breast carcinoma was evaluated by immunohistochemistry. Thirty-seven of 92 carcinomas (40%) were GST P positive. GST P staining did not correlate with histological variables, c-erbB-2 overexpression or with clinical outcome. The GST P status of recurrences did not correlate with that of the index lesion. There is little evidence that GST P is a useful marker of the potential of intraduct breast carcinoma to become invasive.
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Bellamy, C., Harrison, D. Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast. Br J Cancer 69, 183–185 (1994). https://doi.org/10.1038/bjc.1994.31
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DOI: https://doi.org/10.1038/bjc.1994.31
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