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Circadian Periodicity of Blood Amino-acids in Normal and Adrenalectomized Mice

Abstract

THE total amino-acid concentration of healthy young men varies considerably with the time of day1,2. The periodicity of eighteen amino-acids in healthy adult males has been reported and the factors affecting their periodicity discussed3. Investigation of the regulation of plasma amino-acid rhythm through the corticoid rhythm was thought to be imperative4. We report a circadian periodicity for blood amino-acids in mice as well as the effect of adrenalectomy on the observed rhythmicity.

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FEIGIN, R., DANGERFIELD, H. & BEISEL, W. Circadian Periodicity of Blood Amino-acids in Normal and Adrenalectomized Mice. Nature 221, 94–95 (1969). https://doi.org/10.1038/221094a0

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