PAPS PapersEarly experience with PET/CT scan in the evaluation of pediatric abdominal neoplasms
Section snippets
Methods
Children who underwent FDG PET/CT in the workup of abdominal neoplasms between July 2005 and January 2008 were identified. Retrospective review of the radiology reports, operative notes, and pathology reports was undertaken. Institutional review board approval was obtained. Information obtained from radiology reports included preoperative or postoperative timing of the study, location of primary tumor as well as the presence of metastatic disease. Avidity of the primary as well as metastatic
Results
A total of 36 patients were collected. These included Burkitt's lymphoma (8), neuroblastoma (7), rhabdomyosarcoma (6): abdominal wall, biliary, prostatic [2], paraspinal, and paratesticular), ovarian tumor (3): dysgerminoma [2], granulosa cell tumor [1]), Wilms' tumor (2), hepatocellular carcinoma (2), undifferentiated sarcoma (1): postradiotherapy for neuroblastoma), metastatic germ cell tumor (1), gastrointestinal stromal tumor (1), adrenocortical carcinoma (1), renal primitive
Discussion
The PET scan has been increasingly incorporated into diagnostic and follow-up protocols of adult and pediatric malignancies, especially in lymphomas and sarcomas [3], [4], [5]. The PET/CT scan in pediatric sarcoma was found to have a high sensitivity (92%) in the detection of malignant sites, similar to results reported in adult patients [3]. In December 2007, Volker [4] reported one of the few prospective studies using PET scan in pediatric sarcoma. The study included 46 patients (Ewing's
References (8)
- et al.
Application of annihilation coincidence detection to transaxial reconstruction tomography
J Nucl Med
(1975) - et al.
A combined PET/CT scanner for clinical oncology
J Nucl Med
(2000) Positron emission tomography/computed tomography with 18fluoro-deoxyglucose in the detection of local recurrence and distant metastases of pediatric sarcoma
Pediatr Blood Cancer
(2007)- et al.
Positron emission tomography for staging of pediatric sarcoma patients: results of a prospective multi-center trial
J Clin Oncol
(2007)
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Neuroblastoma: MIBG Imaging and New Tracers
2017, Seminars in Nuclear MedicineCitation Excerpt :There is strong evidence that initial staging of neuroblastoma (NB) remains decisive regarding risk-stratification to choose the most appropriate treatment option.3,8 Imaging of NB consists of sonography, computed tomography (CT), magnetic resonance imaging (MRI), and radionuclide examinations such as scintigraphic bone scanning, metaiodobenzylguanidine (MIBG) scintigraphy, positron emission tomography (PET) with different tracers (primarily fluorodeoxyglucose [FDG]), and recently hybrid imaging (PET/CT, SPECT/CT, and PET/MRI).9-21 The therapeutic spectrum depends upon clinical stage and consists of supportive care with no treatment (stage IVS), definitive excision if possible, or chemotherapy before and after surgery partially combined with total-body irradiation and MIBG therapy, followed by autologous bone marrow transplantation.4,6,22,23
Renal primitive neuroectodermal tumor
2012, Journal of UrologyFollow-up of acute osteomyelitis in children: The possible role of PET/CT in selected cases
2011, Journal of Pediatric SurgeryCitation Excerpt :The possible role of PET/CT scan as a tool for establishing the diagnosis initially should also be clarified. Increasing experience with FDG PET and PET/CT exists for various conditions; some of them also contain data on children [29-34,39,40]. However, there are no reports, thus far, in which the diagnostic workup or follow-up of acute osteomyelitis have been assessed using PET/CT in children.
Adrenal masses in children
2011, Radiologic Clinics of North AmericaCitation Excerpt :Imaging diagnosis is more accurate when anatomic images, provided by CT, and metabolic images, provided by PET, are fused, compared with PET alone, or in a side-by-side comparison of PET and CT images.19,20 In recent years, several papers have shown the high impact of PET and PET-CT in the oncologic management of the pediatric patient population as well.2,3,5 Furthermore, in addition to the use of CT, MIBG scintigraphy and fludeoxyglucose (FDG) PET-CT have been found to play an important role in the follow-up after surgery and/or chemotherapy.
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Presented at the 41st annual meeting of the Pacific Association of Pediatric Surgeons, Jackson Lodge, Grand Teton National Park, Wyoming, June 29-July 3, 2008.