Short communicationMicroPET detection of enhanced 18F-FDG utilization by PKA inhibitor in awake rat brain
References (10)
- et al.
The role of the cAMP-PKA system in the short-term regulation of striatal [(14)C]-2-deoxyglucose uptake in freely moving rats
Brain Res.
(2001) - et al.
Real-time monitoring of brain energy metabolism in vivo using microelectrochemical sensors: the effects of anesthesia
Bioelectrochemistry
(2001) - et al.
Assessment of microPET performance in analyzing the rat brain under different types of anesthesia: comparison between quantitative data obtained with microPET and ex vivo autoradiography
NeuroImage
(2003) - et al.
Interference of anaesthetics with radioligand binding in neuroreceptor studies
Eur. J. Nucl. Med. Mol. Imaging
(2003) - et al.
Efficient stereospecific synthesis of no-carrier-added 2-[18F]-fluoro-2-deoxy-d-glucose using aminopolyether supported nucleophilic substitution
J. Nucl. Med.
(1986)
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2017, Comprehensive Toxicology: Third EditionA voxel-based analysis of brain activity in high-order trigeminal pathway in the rat induced by cortical spreading depression
2015, NeuroImageCitation Excerpt :Because FDG is taken up and remains within activated regions during conscious conditions, it can be imaged at the end of the uptake period for a short time while the animal is under anesthesia (Jang et al., 2009; Schiffer et al., 2007; Sung et al., 2009; Thompson and Bushnell, 2012). It is well known that anesthesia affects various neural responses, including pain transmission and perception (Hosoi et al., 2005; Onoe et al., 1994). In the present study, we successfully revealed brain activity in the conscious rat and identified activated brain regions in response to cortical SD, which may display migraine pain transmission and perception.
Towards a reproducible protocol for repetitive and semi-quantitative rat brain imaging with <sup>18</sup> F-FDG: Exemplified in a memantine pharmacological challenge
2014, NeuroImageCitation Excerpt :Small animal 18 F-FDG PET allows us to study glucose metabolism longitudinally in vivo in laboratory animals (Backes et al., 2011; Dedeurwaerdere et al., 2005; Fueger et al., 2006a; Hosoi et al., 2005; Jang et al., 2009; Lee et al., 2005; Nguyen et al., 2012; Sung et al., 2009; Wong et al., 2011).
Molecular imaging in neuroscience research with small-animal PET in rodents
2011, Neuroscience ResearchCitation Excerpt :To overcome the shortcomings of anesthesia, a few studies have been carried out to image conscious rodents by using a head-fixation device. Hosoi et al. (2005) developed a head-fixation system that has proved valuable for measuring glucose metabolism in the conscious rat brain. Recently, Mizuma et al. (2010) developed an in vivo imaging system in conscious mice, using a head-fixation device, to perform quantitative kinetic analysis of regional cerebral glucose metabolic rate.
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