Original articleGeneral thoracicPositron Emission Tomography–Computed Tomography in Predicting Locoregional Invasion in Esophageal Squamous Cell Carcinoma
Section snippets
Patients and Methods
This retrospective analysis was based on prospectively collected data. From March 2007 to December 2008, 200 patients with esophageal cancer were admitted to the division of thoracic surgery of the department of surgery at Taipei-Veterans General Hospital. The staging workup included physical examination, laboratory tests, esophagogastroduodenoscopy, flexible bronchoscopy, barium esophagography, CT scan from neck to upper abdomen, and whole body PET/CT. Patients without distant metastasis or
Tumor Invasion Depth
The patient characteristics are summarized in Table 1. The mean SUVmax of the primary tumor was 11.64 ± 5.00 (range, 0 to 23.00). The mean SUVmax of the primary tumor in patients grouped according to T stage was 5.09 ± 4.00 for T1 lesions, 14.17 ± 2.46 for T2; 13.32 ± 3.96 for T3, and 10.37 ± 1.94 for T4. The SUVmax was significantly lower for T1 stage tumors than for T2 and T3 stage tumors (T1 versus T2, p = 0.001; T1 versus T3, p < 0.001). We further stratified patients into two groups using
Comment
Although many studies suggest the value of FDT-PET or PET/CT in staging as well as prediction of treatment response and prognosis, the results for esophageal cancer have been contradictory [2, 5, 6]. Van Westreenen and associates [14] reported high false positive (7.5%) and false negative (4.5%) rates for FDG-PET in detecting distant metastasis. They also proposed that FDG-PET has a limited role in staging esophageal cancer, especially in patients with early tumors [14]. A study by Gillham and
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2022, Journal of the American College of RadiologyContribution of PET-CT in radiotherapy planning of oesophageal carcinoma: A review
2013, RadiographyCitation Excerpt :Two studies were originally published in other languages (bilingual abstracts)23,24 but they had English equivalents so were included. Another 15 articles were excluded due to an overlap in study population,25–28 missing essential data,29–33 inappropriate reference standard34,35 and administration of chemotherapy before re-staging or RT planning.36–39 Finally, only 37 studies were included in this review.40–76