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Relation of left ventricular sphericity to 10-year survival after acute myocardial infarction

https://doi.org/10.1016/j.amjcard.2004.07.110Get rights and content

After ST-elevation myocardial infarction, the association between left ventricular sphericity (measured by biplane ventriculography) and survival rate at a median of 6.5 years was determined in 825 patients. The highest tertileof sphericity (vs the lowest and middle tertiles) was associated with a decreased 10-year survival rate in patients who had anterior myocardial infarction (p = 0.002), inferior myocardial infarction (p = 0.011), Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow (p = 0.005), or TIMI grade 0 to 2 flow (p = 0.001) in the infarct artery. The independent multivariate predictors of a 10-year survival rate were ejection fraction (p = 0.002), treadmill exercise duration (p = 0.004), biplane left ventricular sphericity index (p = 0.032), age (p = 0.043), and end-systolic volume index (p = 0.047), but not TIMI flow grade.

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Acknowledgment

The investigators gratefully acknowledge the statistical advice of John Simes, the technical assistance of Bruce Webber, the secretarial support of Charlene Nell, and the editorial assistance of Anna Breckon.

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This study was supported in part by grant 910 from the National Heart Foundation of New Zealand, Auckland, New Zealand.Professor White received partial salary funding from the Green Lane Hospital Research and Educational Fund, Auckland, New Zealand.

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