Clinical InvestigationImaging and Diagnostic TestingMulti–detector row cardiac computed tomography accurately quantifies right and left ventricular size and function compared with cardiac magnetic resonance
Section snippets
Patient enrollment
Individuals with known or suspected coronary disease were prospectively recruited as part of a multimodality investigation of atherosclerosis. Written informed consent was obtained for participation in this institutional review board–approved protocol. Exclusion criteria included age <18 years, allergy to iodinated contrast, renal insufficiency (serum creatinine >1.5 mg/dL), pregnancy, presence of ferrous metal in the body or other MR-incompatible implant, and severe claustrophobia. Cardiac CT
Results
Twenty-six subjects were sequentially enrolled; unanticipated claustrophobia precluded MR examination in one subject and CT image reconstruction could not be completed in another subject because of nongated acquisition. Thus, 24 subjects successfully underwent both cardiac CT and CMR examinations; clinical characteristics of the study population are summarized in Table I. The mean HR during helical CT acquisition ranged from 47 to 72 beat/min, whereas HR during CMR short-axis cine imaging
Discussion
In this work, we found excellent agreement between multi–detector row cardiac CT and CMR measurements of both RV and LV size and function. Semiautomated analysis software facilitated detection of endocardial and epicardial borders and calculations of ventricular measurements. Such measurements help guide individual patient management and are usually derived from other diagnostic procedures such as echocardiography or ventriculography, although with less precision and accuracy compared with CMR.
References (21)
- et al.
Quantification of right ventricular function with magnetic resonance imaging in children with normal hearts and with congenital heart disease
Am Heart J
(1995) - et al.
Surgical ventricular restoration in the treatment of congestive heart failure due to post-infarction ventricular dilation
J Am Coll Cardiol
(2004) - et al.
Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy
Am J Cardiol
(2002) - et al.
Usefulness of multi–detector row computed tomography to quantify right ventricular size and function in adults with either tetralogy of Fallot or transposition of the great arteries
Am J Cardiol
(2005) - et al.
Advances in cardiac imaging with 16-section CT systems
Acad Radiol
(2003) - et al.
ACC/AHA guidelines for the management of patients with valvular heart disease. A report of the American College of Cardiology/American Heart Association. Task Force on Practice Guidelines (Committee on Management of Patients with Valvular Heart Disease)
J Am Coll Cardiol
(1998) - et al.
Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction
Circulation
(1987) - et al.
Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications
Circulation
(1990) - et al.
Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators
N Engl J Med
(1996) - et al.
Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction: improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators
N Engl J Med
(2002)
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This study was supported by a grant from the State of Ohio (BRTT02-0022).