Scientific paper8:45—9:00: Using PET 18F-FDG, 11CO, and 15O-water for Monitoring Prostate Cancer During a Phase II Anti-angiogenic Drug Trial with Thalidomide
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Imaging of prostate cancer with PET/CT and radioactively labeled choline derivates
2013, Urologic Oncology: Seminars and Original InvestigationsCitation Excerpt :In current literature, very few papers from few patients under anti-androgenic therapy are reported. Preliminary results with 18F-FDG PET [61,62], 18F-FCH PET [63], and 11C-choline PET/CT [25] revealed a significant decrease of tracer uptake after initiation of anti-androgenic therapy. Giovacchini et al. (2008) monitored a group of 6 patients with localized prostate cancer of a median Gleason score equal to 6 (range 5–7) under bicalutamide treatment (150 mg/d) for a median time of 4 months (range 3–12 months) by 11C-choline PET/CT.
Thalidomide
2004, LancetCitation Excerpt :However, dose escalation over 600 mg in this elderly cohort was rare. Improvements in measurable disease by bone scan and positron emission tomography114 were also noted in some responsive patients. In another study115 in men with androgen independent prostate cancer, thalidomide 100 mg per day resulted in a fall in prostate specific antigen in 15% of patients, with VEGF and basic fibroblast growth factor serum concentrations correlating with progression and favourable response, respectively.
Anti-angiogenesis in cancer therapy
2003, Seminars in Oncology NursingCurrent status of thalidomide and its role in the treatment of metastatic prostate cancer
2003, Critical Reviews in Oncology/HematologyAngiogenesis and apoptosis
2003, Seminars in Cancer BiologyErythrocytes labeled with [<sup>18</sup>F]SFB as an alternative to radioactive CO for quantification of blood volume with PET
2013, Contrast Media and Molecular Imaging