Elsevier

Academic Radiology

Volume 4, Issue 1, January 1997, Pages 1-7
Academic Radiology

Original investigation
Mixture distribution and receiver operating characteristic analysis of bedside chest imaging with screen-film and computed radiography

https://doi.org/10.1016/S1076-6332(97)80152-3Get rights and content
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Rationale and Objectives.

The authors demonstrated the use of mixture distribution analysis as an alternative to receiver operating characteristic (ROC) analysis in a clinical study, where independent verification of the imaging diagnosis is not always feasible.

Methods.

ROC and mixture distribution analyses were applied to the blind readings of four radiologists on a stratified, random sample of 95 screen-film radiographs and 95 computed radiographs of the chest obtained from a medical intensive care unit. The imaging diagnosis established by an expert panel was used as the truth for the ROC analysis, and agreement of ratings was used for the mixture distribution analysis.

Results.

Both methods yielded similar values for the proportion of correct diagnoses.

Conclusion.

Mixture distribution analysis may be useful for comparing imaging techniques in situations where the true imaging diagnosis cannot be established with a method independent of that being evaluated.

Key Words

Technology evaluation
mixture distribution analysis
receiver operating characteristic analysis
bedside chest radiography
computed radiography

Cited by (0)

This work was supported by grant CA 53141 from the National Cancer Institute, National Institutes of Health, U.S. Public Health Service, Department of Health and Human Services.