Original articleEvaluation of myocardial infarct size in rat heart by pinhole SPECT☆
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Cited by (40)
A Monte Carlo study on the performance evaluation of a parallel hole collimator for a HiReSPECT: A dedicated small-animal SPECT
2018, Applied Radiation and IsotopesCitation Excerpt :Also, the collimator has a significant effect on sensitivity and spatial resolution of a imaging system in a small field of view (FOV) (Azarm et al., 2015). A number of small animal SPECT imaging systems have been developed based on the pinhole or multi-pinhole collimation (Hirai et al., 2000; Hsu and Huang, 2006; Min et al., 2011; Nuyts et al., 2009; Weber et al., 1994). The studies have shown that pinholes provide lower sensitivity and detectability than parallel hole collimators (Velden et al., 2017).
Design and development of a high resolution animal SPECT scanner dedicated for rat and mouse imaging
2014, Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated EquipmentCitation Excerpt :In this way, there are significant advancements happening both on the instrumentation front for data acquisition and in the development of reconstruction methods for extracting images from the acquired data. Most small animal SPECT systems have been developed based on pinhole or multi-pinhole collimation technique as reported in the literature [10–15]. Few dedicated small animal systems have been designed and developed based on parallel-hole collimation system.
Role of Intact Biological Models for Evaluation of Radiotracers
2010, Clinical Nuclear Cardiology: State of the Art and Future DirectionsRole of intact biological models for evaluation of radiotracers
2010, Clinical Nuclear CardiologyReal-Time Myocardial Contrast Echocardiography in Rat: Infusion Versus Bolus Administration
2009, Ultrasound in Medicine and BiologyCitation Excerpt :For most of these studies, the information of myocardial microcirculation is very important (Lahoutte 2007). Many strategies have been used to evaluate myocardial perfusion, including cardiac magnetic resonance imaging and nuclear imaging techniques (Nahrendorf et al. 2000; Hirai et al. 2000). However, these techniques are limited by their expense, the sophisticated equipment they require.
Monitoring left ventricular function in small animals
2007, Journal of Nuclear CardiologyCitation Excerpt :This duration is acceptable for repeated small animal studies and is within the limits of the length of single-dose intraperitoneal anesthesia by use of barbiturates. Ungated SPECT imaging of myocardial perfusion in both rats and mice has been performed by several research groups.15,22-26 Both thallium 201 and Tc-99m–labeled isonitrile complexes (Tc-99m methoxyisobutylisonitrile and Tc-99m tetrofosmin) have been used.
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Presented at the Third International Conference of Nuclear Cardiology, Florence, Italy, 6–9 April, 1997.