Brain functional activity during gait in normal subjects: a SPECT study

doi:10.1016/S0304-3940(97)00381-9

Neuroscience Letters

Volume 228, Issue 3, 13 June 1997, Pages 183-186

https://doi.org/10.1016/S0304-3940(97)00381-9 Get rights and content

Abstract

The purpose of this study was to evaluate changes in brain activity during voluntary walking in normal subjects using technetium-99m-hexamethyl-propyleneamine oxime single photon emission computed tomography. This study included 14 normal subjects. Statistical parametric mapping analysis revealed that the supplementary motor area, medial primary sensorimotor area, the striatum, the cerebellar vermis and the visual cortex were activated. These results suggested that the cerebral cortices controlling motor functions, visual cortex, basal ganglia and the cerebellum might be involved in the bipedal locomotor activities in humans.

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Acknowledgements

Dr. H. Fukuyama was supported by Takeda Medical Research Foundation. This study was partly supported by Grants-in-Aid for Scientific Research (A) 06404031, for Scientific Research on Priority Area 08279106, and for International Scientific Research 07044258 from the Japan Ministry of Education, Science, Sports and Culture, and Research Grant for Nervous and Mental Disorders `Functional Imaging' from the Japan Ministry of Health and Welfare.

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Brain functional activity during gait in normal subjects: a SPECT study

Abstract

Section snippets

Acknowledgements

Brain Res.

J. Neurol. Sci.

Quantitative measurements of cerebral blood flow using SPECT and [99mTc]-d,l-HM-PAO compared to Xe-133

J. Cerebral Blood Flow Metab.

Motor cortical activity during voluntary gait modifications in the cat. I. Cells related to the forelimbs

J. Neurophysiol.

Comparing function (PET) images: the assessment of significant change

J. Cerebral Blood Flow Metab.

Plastic transformation of PET images

J. Comput. Assist. Tomogr.

Locomotion in vertebrates: central mechanisms and reflex interaction

Physiol. Rev.

Brain function associated with bipedal gait – A PET study

J. Cerebral Blood Flow Metab.

Nucleus accumbens to globus pallidus GABA projection subserving ambulatory activity

Am. J. Physiol.

Quantitative measurements of cerebral blood flow using SPECT and [^99mTc]-d,l-HM-PAO compared to Xe-133