Catecholamine cardiotoxicity
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2022, Regenerative TherapyCitation Excerpt :Isoproterenol [1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride] is a synthetic material with catecholamine property and β-adrenergic agonist has dual effects at different doses. It can create severe myocardial infraction at high doses and induce heart function improvement at low doses [2,3]. Myocardial necrosis was created after cardiac dysfunction at high dose Isoproterenol via increase peroxidation of myocardial lipids by alterations in cardiac enzymes and antioxidants [4,5].
Copyright © 1985 Published by Elsevier Ltd.