Research paperPET imaging of opiate receptor binding in human epilepsy using [18F]cyclofoxy
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2015, SeizureCitation Excerpt :Among cases undergoing invasive EEG monitoring, surgical outcomes of PET-positive cases are better. Invasive EEG monitoring is gold standard when there are difficulties or conflicts in noninvasive assessments [24–27]. The demonstration that excellent surgical outcomes are achieved in TLE cases, if IED and ictal EEG findings on noninvasive EEG are consistent with PET findings has led to a new understanding [15,28,29].
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2012, Handbook of Clinical NeurologyCitation Excerpt :However, increased binding of the delta-receptor-selective antagonist was present in mid-inferior and anterior aspects of the middle and superior temporal cortex (Madar et al., 1997). [ 18F]cyclofoxy, a mu- and kappa-receptor antagonist, showed no group asymmetry (Theodore et al., 1992a). Kappa-receptor downregulation might offset mu-receptor upregulation.