An application of Acridine Orange fluorescent staining to the micronucleus test

doi:10.1016/0165-7992(83)90096-9

Mutation Research Letters

Volume 120, Issue 4, June 1983, Pages 241-247

https://doi.org/10.1016/0165-7992(83)90096-9 Get rights and content

Abstract

Acridine Orange fluorescent staining was applied to the micronucleus test in mice and rats. Micronuclei emitted bright green fluorescence and were easily distinguished from micronucleus-like inclusions or contaminants. In rat bone-marrow cells, micronuclei with green fluorescence could be easily distinguished from granules accidentally dispersed from broken mast cells, which showed bright red fluorescence.

Therefore, it is recommended that the Acridine Orange staining method be used to provide more reliable data in the micronucleus test.

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There are more references available in the full text version of this article.

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An application of Acridine Orange fluorescent staining to the micronucleus test

Abstract

Mutation Res.

Mutation Res.

Int. Rev. Cytol.

Mutation Res.