Somatostatin receptor subtype gene expression in human and rodent tumors
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VIP as a trophic factor in the CNS and cancer cells
2003, PeptidesA targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice
2001, European Journal of CancerCitation Excerpt :The expression of SST receptors by non-SCLC remains controversial. While non-SCLC are described by many investigators as SST receptor- negative cancers [12,13,32,33], Eden and Taylor [34] detected mRNA for SST receptor subtype 2 in two non-SCLC cell lines. Adding to the complexity of the issue, Siegfried and colleagues [35] recently showed that under certain conditions, non-SCLC may acquire characteristics, such as the expression of gastrin releasing peptide (GRP), a hormone associated with the growth of various tumours including SCLC.
Characterisation of somatostatin sst<inf>2</inf> receptor splice variants
2000, Journal of Physiology ParisExpression of somatostatin receptor subtype 2 mRNA in human lymphoid cells
1997, Cellular Immunology
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