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Creation and characterization of Japanese standards for myocardial perfusion SPECT: database from the Japanese Society of Nuclear Medicine Working Group

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Abstract

Objective

Standards for myocardial single-photon emission computed tomography (SPECT) adapted for a Japanese population were not available. The purpose of this study was to create standard files approved by the Japanese Society of Nuclear Medicine and to make known the characteristics of the myocardial perfusion pattern of this population.

Methods

With the collaboration of nine hospitals, a total of 326 sets of exercise–rest myocardial perfusion images were accumulated from subjects with a low likelihood of cardiac diseases. The normal database included a 99mTc-MIBI/tetrofosmin myocardial perfusion study with 360° (n = 80) and 180° (n = 56) rotations, 201Tl study with 360° (n = 115) and 180° rotations (n = 54) and a dual-isotope study with 360° rotation (n = 27). The projection images were transferred by digital imaging and communications in medicine (DICOM) format and reconstructed and analyzed with polar maps.

Results

The projection data from multiple centers were successfully transferred to a common format for SPECT reconstruction. When the average values were analyzed using a 17-segment model, myocardial counts in the septal segment differed significantly between 180° and 360° rotation acquisitions. Regional differences were observed between men and women in the inferior and anterior regions. A tracer difference between 99mTc and 201Tl was also observed in some segments. The attenuation patterns differed significantly between subjects from the United States and those from Japan.

Conclusions

Myocardial perfusion data that were specific for the Japanese population were generated. The normal database can serve a standard for nuclear cardiology work conducted in Japan.

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References

  1. FJ Klocke MG Baird BH Lorell TM Bateman JV Messer DS Berman et al. (2003) ArticleTitleACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging—executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuclide Imaging) Circulation 108 1404–18 Occurrence Handle12975245 Occurrence Handle10.1161/01.CIR.0000080946.42225.4D

    Article  PubMed  Google Scholar 

  2. N Tamaki (2005) ArticleTitleGuidelines for clinical use of cardiac nuclear medicine (JCS 2005) Circulation J 69 IssueIDSuppl IV 1125–202

    Google Scholar 

  3. TL Faber CD Cooke RD Folks JP Vansant KJ Nichols EG DePuey et al. (1999) ArticleTitleLeft ventricular function and perfusion from gated SPECT perfusion images: an integrated method J Nucl Med 40 650–9 Occurrence Handle10210225 Occurrence Handle1:STN:280:DyaK1M3isV2gsw%3D%3D

    PubMed  CAS  Google Scholar 

  4. TL Faber CA Santana EV Garcia J Candell-Riera RD Folks JW Peifer et al. (2004) ArticleTitleThree-dimensional fusion of coronary arteries with myocardial perfusion distributions: clinical validation J Nucl Med 45 745–53 Occurrence Handle15136621

    PubMed  Google Scholar 

  5. G Germano DS Berman (2003) Gated myocardial perfusion SPECT V Dilsizian J Narula (Eds) Atlas of nuclear cardiology Current Medicine Philadelphia 167–82

    Google Scholar 

  6. G Germano H Kiat PB Kavanagh M Moriel M Mazzanti HT Su et al. (1995) ArticleTitleAutomatic quantification of ejection fraction from gated myocardial perfusion SPECT J Nucl Med 36 2138–47 Occurrence Handle7472611 Occurrence Handle1:STN:280:BymD2cbhtF0%3D

    PubMed  CAS  Google Scholar 

  7. CS Lipke HP Kuhl B Nowak HJ Kaiser P Reinartz KC Koch et al. (2004) ArticleTitleValidation of 4D-MSPECT and QGS for quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPET: comparison with cardiac magnetic resonance imaging Eur J Nucl Med Mol Imaging 31 482–90 Occurrence Handle14722679 Occurrence Handle10.1007/s00259-003-1411-y

    Article  PubMed  Google Scholar 

  8. DP Lum MN Coel (2003) ArticleTitleComparison of automatic quantification software for the measurement of ventricular volume and ejection fraction in gated myocardial perfusion SPECT Nucl Med Commun 24 259–66 Occurrence Handle12612466 Occurrence Handle10.1097/00006231-200303000-00005 Occurrence Handle1:STN:280:DC%2BD3s7gtVWrug%3D%3D

    Article  PubMed  CAS  Google Scholar 

  9. K Nakajima T Higuchi J Taki M Kawano N Tonami (2001) ArticleTitleAccuracy of ventricular volume and ejection fraction measured by gated myocardial SPECT: comparison of 4 software programs J Nucl Med 42 1571–8 Occurrence Handle11585875 Occurrence Handle1:STN:280:DC%2BD3MrjvFSrsg%3D%3D

    PubMed  CAS  Google Scholar 

  10. K Nichols CA Santana R Folks E Krawczynska CD Cooke TL Faber et al. (2002) ArticleTitleComparison between ECTb and QGS for assessment of left ventricular function from gated myocardial perfusion SPECT J Nucl Cardiol 9 285–93 Occurrence Handle12032476 Occurrence Handle10.1067/mnc.2002.121449

    Article  PubMed  Google Scholar 

  11. H Nishina PJ Slomka A Abidov S Yoda C Akincioglu X Kang et al. (2006) ArticleTitleCombined supine and prone quantitative myocardial perfusion SPECT: method development and clinical validation in patients with no known coronary artery disease J Nucl Med 47 51–8 Occurrence Handle16391187

    PubMed  Google Scholar 

  12. PJ Slomka H Nishina DS Berman X Kang JD Friedman SW Hayes et al. (2004) ArticleTitleAutomatic quantification of myocardial perfusion stress-rest change: a new measure of ischemia J Nucl Med 45 183–91 Occurrence Handle14960634

    PubMed  Google Scholar 

  13. K Nakajima T Nishimura (2006) ArticleTitleInter-institution preference-based variability of ejection fraction and volumes using quantitative gated SPECT with 99 mTc-tetrofosmin: a multicentre study involving 106 hospitals Eur J Nucl Med Mol Imaging 33 127–33 Occurrence Handle16193310 Occurrence Handle10.1007/s00259-005-1916-7

    Article  PubMed  Google Scholar 

  14. K Nakajima H Kusuoka S Nishimura A Yamashina T Nishimura (2007) ArticleTitleNormal limits of ejection fraction and volumes determined by gated SPECT in clinically normal patients without cardiac events: a study based on the J-ACCESS database Eur J Nucl Med Mol Imaging 34 1088–96 Occurrence Handle17219133 Occurrence Handle10.1007/s00259-006-0321-1

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa, 920-8641, Japan

    Kenichi Nakajima, Shinichiro Kumita, Yoshio Ishida, Mitsuru Momose, Jun Hashimoto, Koichi Morita, Junichi Taki, Shohei Yamashina, Hirotaka Maruno, Masami Ogawa, Masahiro Kubota, Munehiro Takahashi, Tetsuro Odagawa & Koichi Yokozuka

Authors
  1. Kenichi Nakajima
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  2. Shinichiro Kumita
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  3. Yoshio Ishida
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  4. Mitsuru Momose
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  5. Jun Hashimoto
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  6. Koichi Morita
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  7. Junichi Taki
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  8. Shohei Yamashina
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  9. Hirotaka Maruno
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  10. Masami Ogawa
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  11. Masahiro Kubota
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  12. Munehiro Takahashi
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  13. Tetsuro Odagawa
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  14. Koichi Yokozuka
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Corresponding author

Correspondence to Kenichi Nakajima.

Additional information

All author are members of the JSNM Working Group of Standardization of Myocardial SPECT in a Japanese Population.

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Nakajima, K., Kumita, S., Ishida, Y. et al. Creation and characterization of Japanese standards for myocardial perfusion SPECT: database from the Japanese Society of Nuclear Medicine Working Group. Ann Nucl Med 21, 505–511 (2007). https://doi.org/10.1007/s12149-007-0059-2

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  • DOI: https://doi.org/10.1007/s12149-007-0059-2

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