Abstract
Purpose
Some patients cannot remain immobile for a long duration of 60 min, which is generally applied in the case of a 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) dynamic positron emission tomography (PET) scan. We investigated the change of the parametric values when the time duration of PET data was shortened.
Procedures
Eight normal subjects and four subjects with brain glioma were studied. The rate values of K 1, k 2, k 3, and K i parametric images were computed by changing the time duration from 20 to 60 min, and changes of those parametric values were compared.
Results
The change was 20–30% and 3–5% for k 3 and K i, respectively, when the scan time was shortened from 60 to 40 min. The ratios of normal and disease regions in k 3 and K i values were similar, and contrasts of those images were not changed when the scan time was shortened to 40 min.
Conclusions
These results demonstrate that the short time duration of [18F]FDG PET examination can provide an acceptable estimation of parametric k 3 and K i images.
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Acknowledgment
The authors thank Dr. Vesa Oikonen in Turku PET Centre in Finland for the instructions and help in using the software for data computation in the present study.
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The authors declare to have no conflicts of interest.
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Monden, T., Kudomi, N., Sasakawa, Y. et al. Shortening the Duration of [18F]FDG PET Brain Examination for Diagnosis of Brain Glioma. Mol Imaging Biol 13, 754–758 (2011). https://doi.org/10.1007/s11307-010-0384-z
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DOI: https://doi.org/10.1007/s11307-010-0384-z