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Evaluation of highly loaded low specific activity 99Mo on alumina column as 99mTc generator

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Abstract

Adsorption behavior of molybdate on acidic alumina was studied at boiling water bath temperature (~100 °C). Various parameters affecting the adsorption of molybdenum, such as pH, amount of molybdenum, incubation period, etc., were determined. A 99mTc generator was prepared by adsorbing low specific activity 99Mo (150 mg) on 1 g alumina. Elutions were carried out with saline. Performance of the generator such as 99Mo breakthrough, aluminum contents, pH, elution profile, radiochemical purity, and labeling efficiency of kits were checked.

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Acknowledgments

The research was performed under an IAEA funded CRP on “Establish Techniques for Small-Scale, Indigenous Production of 99Mo Using Low-Enriched Uranium (LEU) or Neutron Activation” PAK/13320.

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  1. Isotope Production Division, Pakistan Institute of Nuclear Science and Technology, P.O. Nilore, Islamabad, Pakistan

    M. Asif & A. Mushtaq

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  1. M. Asif
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  2. A. Mushtaq
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Correspondence to A. Mushtaq.

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Asif, M., Mushtaq, A. Evaluation of highly loaded low specific activity 99Mo on alumina column as 99mTc generator. J Radioanal Nucl Chem 284, 439–442 (2010). https://doi.org/10.1007/s10967-010-0490-z

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  • DOI: https://doi.org/10.1007/s10967-010-0490-z

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