Abstract
Object
The aim of this study was to determine the impact to PET quantification, image quality and possible diagnostic impact of an anterior surface array used in a combined PET/MR imaging system.
Materials and methods
An extended oval phantom and 15 whole-body FDG PET/CT subjects were re-imaged for one bed position following placement of an anterior array coil at a clinically realistic position. The CT scan, used for PET attenuation correction, did not include the coil. Comparison, including liver SUVmean, was performed between the coil present and absent images using two methods of PET reconstruction. Due to the time delay between PET scans, a model was used to account for average physiologic time change of SUV.
Results
On phantom data, neglecting the coil caused a mean bias of −8.2 % for non-TOF/PSF reconstruction, and −7.3 % with TOF/PSF. On clinical data, the liver SUV neglecting the coil presence fell by −6.1 % (±6.5 %) for non-TOF/PSF reconstruction; respectively −5.2 % (±5.3 %) with TOF/PSF. All FDG-avid features seen with TOF/PSF were also seen with non-TOF/PSF reconstruction.
Conclusion
Neglecting coil attenuation for this anterior array coil results in a small but significant reduction in liver SUVmean but was not found to change the clinical interpretation of the PET images.
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Acknowledgments
The authors would like to thank Prof. G. K. von Schulthess and collaborators at the University Hospital of Zurich for collection of and access to the patient data used in this study.
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Wollenweber, S.D., Delso, G., Deller, T. et al. Characterization of the impact to PET quantification and image quality of an anterior array surface coil for PET/MR imaging. Magn Reson Mater Phy 27, 149–159 (2014). https://doi.org/10.1007/s10334-013-0388-1
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DOI: https://doi.org/10.1007/s10334-013-0388-1