Abstract
The domestic dog (Canis familiaris) shows greater phenotypic variation than any other mammal. A corollary of this variation has been the recognition of more naturally occurring inherited diseases in dogs than have been cataloged in any other species apart from man. Recent catalogs list more than 370. A searchable Web-based database “Inherited Diseases in Dogs” (http://www.vet.cam.ac.uk/idid) has been developed. It catalogs diseases and conditions of dogs which are likely to be transmitted wholly or partly through a genetic mechanism, together with breeds in which they have been described. It contains disease listings and short descriptions, genetic and molecular genetic summaries where known, and connects to entry points to the literature on each disease.
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References
EA Ostrander F Galibert DF Patterson (2000) ArticleTitleCanine genetics comes of age Trends Genet 16 117–124 Occurrence Handle10.1016/S0168-9525(99)01958-7 Occurrence Handle1:CAS:528:DC%2BD3cXhsFOisL0%3D Occurrence Handle10689352
DF Patterson (2000) ArticleTitleCompanion animal medicine in the age of medical genetics J Vet Intern Med 14 1–9 Occurrence Handle10.1111/j.1939-1676.2000.tb01492.x Occurrence Handle1:STN:280:DC%2BD3c7jt1antg%3D%3D Occurrence Handle10668810
M Brooks DR Sargan (2001) Chapter 9: Aspects of Genetic Disease A Ruvinsky J Sampson (Eds) Canine Genetics CABI Oxford 191–266
EF Kirkness V Bafna AL Halpern S Levy K Remington et al. (2003) ArticleTitleThe dog genome: survey sequencing and comparative analysis Science 301 IssueID5641 1898–1903 Occurrence Handle10.1126/science.1086432 Occurrence Handle14512627
M Breen S Jouquand C Renier CS Mellersh C Hitte et al. (2003) ArticleTitleChromosome-specific single-locus FISH probes allow anchorage of an 1800-marker integrated radiation-hybrid/linkage map of the domestic dog genome to all chromosomes Genome Res 11 IssueID10 1784–1795 Occurrence Handle10.1101/gr.189401
R Guyon TD Lorentzen C Hitte L Kim E Cadieu et al. (2003) ArticleTitleA 1-Mb resolution radiation hybrid map of the canine genome Proc Natl Acad Sci USA 100 IssueID9 5296–5301 Occurrence Handle10.1073/pnas.0831002100 Occurrence Handle1:CAS:528:DC%2BD3sXjs1yitrc%3D Occurrence Handle12700351
M Breen R Thomas MM Binns NP Carter CF Langford (1999) ArticleTitleReciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog (Canis familiaris) and human Genomics 61 IssueID2 145–155 Occurrence Handle10.1006/geno.1999.5947 Occurrence Handle1:CAS:528:DyaK1MXmslyitrk%3D Occurrence Handle10534400
DR Sargan F Yang M Squire BS Milne PC O‘Brien et al. (2000) ArticleTitleUse of flow-sorted canine chromosomes in the assignment of canine linkage, radiation hybrid, and syntenic groups to chromosomes: refinement and verification of the comparative chromosome map for dog and human Genomics 69 IssueID2 182–195 Occurrence Handle10.1006/geno.2000.6334 Occurrence Handle1:CAS:528:DC%2BD3cXnt1Wjt7s%3D Occurrence Handle11031101
Acknowledgments
The author wishes to acknowledge the help of Dr. Marjory Brooks (James A. Baker Institute of Animal Health, Cornell University) in the initial stages of compiling the content of the database, of Helen Sargan in designing the web interface, and of Janet Smith in helping to populate the databases.
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Sargan, D.R. IDID: Inherited Diseases in Dogs: Web-based information for canine inherited disease genetics. Mamm Genome 15, 503–506 (2004). https://doi.org/10.1007/s00335-004-3047-z
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DOI: https://doi.org/10.1007/s00335-004-3047-z