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The appearances of oesophageal carcinoma demonstrated on high-resolution, T2-weighted MRI, with histopathological correlation

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Abstract

This paper describes the spectrum of imaging features of oesophageal adenocarcinoma seen using high-resolution T2-weighted (T2W) magnetic resonance imaging (MRI). Thirty-nine patients with biopsy-proven oesophageal adenocarcinoma were scanned using an external surface coil. A sagittal T2W sequence was used to localise the tumour and to plan axial images perpendicular to the tumour. Fast spin-echo (FSE) T2W axial sequence parameters were: TR/TE, 3,300–5,000 ms/120–80 ms; field of view (FOV) 225 mm, matrix 176×512(reconstructed) mm to 256×224 mm, giving an in-plane resolution of between 1.28×0.44 mm and 0.88×1.00 mm, with 3-mm slice thickness. Thirty-three patients underwent resection and the MR images were compared with the histological whole-mount sections. There were four T1, 12 T2, and 17 T3 tumours. The T2W high-resolution MRI sequences produced detailed images of the oesophageal wall and surrounding structures. Analysis of the imaging appearances for different tumour T stages enabled the development of imaging criteria for local staging of oesophageal cancer using high-resolution MRI. Our study illustrates the spectrum of appearances of oesophageal cancer on T2W high-resolution MRI, and using the criteria established in this study, demonstrates the potential of this technique as an alternative non-invasive method for local staging for oesophageal cancer.

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Authors and Affiliations

  1. Department of Radiology, Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK

    A. M. Riddell, C. Richardson & G. Brown

  2. Department of Surgery, Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK

    W. H. Allum & J. N. Thompson

  3. Department of Histopathology, Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK

    A. C. Wotherspoon

  4. GI Oncology Imaging Research Fellow, Department of Diagnostic Imaging, The Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK

    A. M. Riddell

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  1. A. M. Riddell
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  2. W. H. Allum
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  3. J. N. Thompson
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  4. A. C. Wotherspoon
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  5. C. Richardson
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  6. G. Brown
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Correspondence to A. M. Riddell.

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Riddell, A.M., Allum, W.H., Thompson, J.N. et al. The appearances of oesophageal carcinoma demonstrated on high-resolution, T2-weighted MRI, with histopathological correlation. Eur Radiol 17, 391–399 (2007). https://doi.org/10.1007/s00330-006-0363-6

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  • DOI: https://doi.org/10.1007/s00330-006-0363-6

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